Funding by INSERM (MESSIDORE call) of the FORECAST project

The FORECAST project coordinated by Julien Kirchgesner has been selected for funding by INSERM (MESSIDORE call) in March 2024.
IBD affects more than 250 000 patients in France and new advanced therapies have been recently marketed. Recent studies support the use of SNDS to study treatment effectiveness in patients with IND, but one of the main limitation is the non-collection in the SNDS of relevant parameters such as disease characteristics (extent and phenotype) and clinical disease activity. 
The objective of this project is to develop a new framework to assess the benefit-risk balance of advanced therapies in IBD using three sources of RWD: the French nationwide healthcare database (Système National des Données de Santé [SNDS]), EHR with the Assistance Publique-Hôpitaux de Paris (EDS AP-HP) Clinical Data Repository, and a prospective cohort of patients with IBD followed in AP-HP centers (SUVIMIC).